同工酶: The human THP-1 cell line expresses low levels of CD4, CCR5, and CxCR4, making it relevant to HIV infection studies. However, they express low levels of CD14 and not CD80, CD86, CD11b, CD11c, Mertk, or CD1a, making them a poor model for primary monocytes regarding LPS responses.
基因表达: lysozyme; HLA: (A2; A9; B5; DRw2)
抗原表达: HLA A2, A9, B5, DRw1, DRw2
核型: THP-1 cells are near-diploid and contain two related subclones with genetic aberrations.
同工酶: The human THP-1 cell line expresses low levels of CD4, CCR5, and CxCR4, making it relevant to HIV infection studies. However, they express low levels of CD14 and not CD80, CD86, CD11b, CD11c, Mertk, or CD1a, making them a poor model for primary monocytes regarding LPS responses.
基因表达: lysozyme; HLA: (A2; A9; B5; DRw2)
抗原表达: HLA A2, A9, B5, DRw1, DRw2
核型: THP-1 cells are near-diploid and contain two related subclones with genetic aberrations.