人乳腺癌细胞

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人乳腺癌细胞(MDA-MB-468)

￥800.00元

细胞货号： CL0211

细胞种属： 人源细胞系

细胞别名： MDA-MB 468; MDA-MB468; MDAMB468; MDA-468; MDA468; MB468; MD Anderson-Metastatic Breast-468

发货规格： 1×10⁶

供体信息： 51岁黑人女性

肿瘤类型： 乳腺癌

组织来源： 乳腺

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背景信息

种属：人源细胞系
组织来源：乳腺
肿瘤类型：乳腺癌
供体信息： 51岁黑人女性
背景描述：成立于1977年，由一名51岁浸润性乳腺癌女性的胸腔积液组成;文献中描述细胞在密码子273处携带p53点突变，导致Arg-His取代和扩增的EGFR;三阴性

培养建议

其他信息

蛋白表达： Epidermalgrowthfactor(EGF);transforminggrowthfactoralpha(TGFalpha)。蛋白质印迹中无ER、PR、AR和HER2证实三阴性
同工酶： AK-1,1；ES-D,1；G6PD,A；GLO-I,1-2；Me-2,1-2；PGM1,1；PGM3,2
致瘤性： Yes, in nude mice inoculated subcutaneously with 10(7) cells.(Tumors developed within 21 days at 100% frequency (5/5).)
抗原表达： Blood Type AB;HLA Aw23,Aw30,B27,Bw35,Cw2,Cw4 (patient)
病毒： EBV-,HBV-,HCV-,HIV-1-,HIV-2-,HTLV-I/-II-,MLV-
核型： modal number = 64; range = 60 to 67.The cell line is aneuploid human, presumably female (X, abnormal X) with most chromosome counts in the hypotriploid range.; Normal chromosomes X, N2, N3, N7, N8, N10, and N22 are clearly under-represented due to their involvement in the formation of the many marker (19) chromosomes present in this cell line.; A normal chromosome N1 (or two) is identified in each karyotype, but, in addition, regions of chromosome N1 are also present in five different marker chromosomes.; Variation is evident in the normal and marker chromosome copy number from karyotype to karyotype.

人乳腺癌细胞

Catalog No CL0211

Product information

蛋白表达： Epidermalgrowthfactor(EGF);transforminggrowthfactoralpha(TGFalpha)。蛋白质印迹中无ER、PR、AR和HER2证实三阴性
同工酶： AK-1,1；ES-D,1；G6PD,A；GLO-I,1-2；Me-2,1-2；PGM1,1；PGM3,2
致瘤性： Yes, in nude mice inoculated subcutaneously with 10(7) cells.(Tumors developed within 21 days at 100% frequency (5/5).)
抗原表达： Blood Type AB;HLA Aw23,Aw30,B27,Bw35,Cw2,Cw4 (patient)
病毒： EBV-,HBV-,HCV-,HIV-1-,HIV-2-,HTLV-I/-II-,MLV-
核型： modal number = 64; range = 60 to 67.The cell line is aneuploid human, presumably female (X, abnormal X) with most chromosome counts in the hypotriploid range.; Normal chromosomes X, N2, N3, N7, N8, N10, and N22 are clearly under-represented due to their involvement in the formation of the many marker (19) chromosomes present in this cell line.; A normal chromosome N1 (or two) is identified in each karyotype, but, in addition, regions of chromosome N1 are also present in five different marker chromosomes.; Variation is evident in the normal and marker chromosome copy number from karyotype to karyotype.

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