核型: Karyotypically, H9 is near triploid with a modal chromosome number of 69, ranging from 58 to 74, and exhibits a 2.5% frequency of higher ploidies. The cell line displays an extremely complex karyotype, with nearly 60% of the chromosomes per cell consisting of structurally altered marker chromosomes, including translocations such as t(3p4q), t(5q6q), t(5p6p), and deletions like del(7)(q32). Such chromosomal abnormalities contribute to the line?s unique genetic profile, influencing its behavior and response to viral infections. The absence of normal chromosomes N4, N5, N6, N7, N10, N13, N18, N19, N20, and X further distinguishes its genetic makeup
核型: Karyotypically, H9 is near triploid with a modal chromosome number of 69, ranging from 58 to 74, and exhibits a 2.5% frequency of higher ploidies. The cell line displays an extremely complex karyotype, with nearly 60% of the chromosomes per cell consisting of structurally altered marker chromosomes, including translocations such as t(3p4q), t(5q6q), t(5p6p), and deletions like del(7)(q32). Such chromosomal abnormalities contribute to the line?s unique genetic profile, influencing its behavior and response to viral infections. The absence of normal chromosomes N4, N5, N6, N7, N10, N13, N18, N19, N20, and X further distinguishes its genetic makeup