储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT1052R
特异性： Endogenous
基因名称： MCM2 BM28 CCNL1 CDCL1 KIAA0030
蛋白名称： DNA replication licensing factor MCM2
别名： MCM2;BM28;CCNL1;CDCL1;KIAA0030;DNA replication licensing factor MCM2;Minichromosome maintenance protein 2 homolog;Nuclear protein BM28
Organism-1： Human
基因ID-1： 4171
SwissProt-1： P49736
Organism-2： Mouse
基因ID-2： 17216
SwissProt-2： P97310
背景： The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012],
细胞定位： Nucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT1052R
特异性： Endogenous
基因名称： MCM2 BM28 CCNL1 CDCL1 KIAA0030
蛋白名称： DNA replication licensing factor MCM2
别名： MCM2;BM28;CCNL1;CDCL1;KIAA0030;DNA replication licensing factor MCM2;Minichromosome maintenance protein 2 homolog;Nuclear protein BM28
Organism-1： Human
基因ID-1： 4171
SwissProt-1： P49736
Organism-2： Mouse
基因ID-2： 17216
SwissProt-2： P97310
背景： The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012],
细胞定位： Nucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .
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