储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT1018R
特异性： Endogenous
基因名称： HK1
蛋白名称： Hexokinase-1
别名： HK1;Hexokinase-1;Brain form hexokinase;Hexokinase type I;HK I
Organism-1： Human
基因ID-1： 3098
SwissProt-1： P19367
Organism-2： Mouse
SwissProt-2： P17710
Organism-3： Rat
基因ID-3： 25058
SwissProt-3： P05708
背景： Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016],
细胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT1018R
特异性： Endogenous
基因名称： HK1
蛋白名称： Hexokinase-1
别名： HK1;Hexokinase-1;Brain form hexokinase;Hexokinase type I;HK I
Organism-1： Human
基因ID-1： 3098
SwissProt-1： P19367
Organism-2： Mouse
SwissProt-2： P17710
Organism-3： Rat
基因ID-3： 25058
SwissProt-3： P05708
背景： Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016],
细胞定位： Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .
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