储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT1029R
特异性： Endogenous
基因名称： PAK2
蛋白名称： Serine/threonine-protein kinase PAK 2
别名： PAK2;Serine/threonine-protein kinase PAK 2;Gamma-PAK;PAK65;S6/H4 kinase;p21-activated kinase 2;PAK-2;p58
Organism-1： Human
基因ID-1： 5062
SwissProt-1： Q13177
Organism-2： Mouse
基因ID-2： 224105
SwissProt-2： Q8CIN4
Organism-3： Rat
基因ID-3： 29432
SwissProt-3： Q64303
背景： The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],
细胞定位： [Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT1029R
特异性： Endogenous
基因名称： PAK2
蛋白名称： Serine/threonine-protein kinase PAK 2
别名： PAK2;Serine/threonine-protein kinase PAK 2;Gamma-PAK;PAK65;S6/H4 kinase;p21-activated kinase 2;PAK-2;p58
Organism-1： Human
基因ID-1： 5062
SwissProt-1： Q13177
Organism-2： Mouse
基因ID-2： 224105
SwissProt-2： Q8CIN4
Organism-3： Rat
基因ID-3： 29432
SwissProt-3： Q64303
背景： The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],
细胞定位： [Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.
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