储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0955R
特异性： Endogenous
基因名称： BIRC2 API1 IAP2 MIHB RNF48
蛋白名称： Baculoviral IAP repeat-containing protein 2 (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)
Organism-1： Human
基因ID-1： 329
SwissProt-1： Q13490
Organism-2： Mouse
SwissProt-2： Q62210
背景： The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
细胞定位： Cytoplasm. Nucleus. Agents that induce either the extrinsic or intrinsic apoptotic pathways promote its redistribution from the nuclear compartment to the cytoplasmic compartment. Associated with the midbody in telophase cells, and found diffusely in the nucleus of interphase cells.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0955R
特异性： Endogenous
基因名称： BIRC2 API1 IAP2 MIHB RNF48
蛋白名称： Baculoviral IAP repeat-containing protein 2 (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (IAP-2) (hIAP-2) (hIAP2) (RING finger protein 48) (TNFR2-TRAF-signaling complex protein 2)
Organism-1： Human
基因ID-1： 329
SwissProt-1： Q13490
Organism-2： Mouse
SwissProt-2： Q62210
背景： The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
细胞定位： Cytoplasm. Nucleus. Agents that induce either the extrinsic or intrinsic apoptotic pathways promote its redistribution from the nuclear compartment to the cytoplasmic compartment. Associated with the midbody in telophase cells, and found diffusely in the nucleus of interphase cells.
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