储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0893R
特异性： Endogenous
基因名称： OLIG2 BHLHB1 BHLHE19 PRKCBP2 RACK17
蛋白名称： OLIG2
别名： Oligodendrocyte transcription factor 2;Oligo2;Class B basic helix-loop-helix protein 1;bHLHb1;Class E basic helix-loop-helix protein 19;bHLHe19;Protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;
Organism-1： Human
基因ID-1： 10215
SwissProt-1： Q13516
Organism-2： Mouse
基因ID-2： 50913
SwissProt-2： Q9EQW6
背景： This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008],
细胞定位： Nucleus . Cytoplasm . The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. .
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0893R
特异性： Endogenous
基因名称： OLIG2 BHLHB1 BHLHE19 PRKCBP2 RACK17
蛋白名称： OLIG2
别名： Oligodendrocyte transcription factor 2;Oligo2;Class B basic helix-loop-helix protein 1;bHLHb1;Class E basic helix-loop-helix protein 19;bHLHe19;Protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;
Organism-1： Human
基因ID-1： 10215
SwissProt-1： Q13516
Organism-2： Mouse
基因ID-2： 50913
SwissProt-2： Q9EQW6
背景： This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008],
细胞定位： Nucleus . Cytoplasm . The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2. .
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