储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0877R
特异性： Endogenous
基因名称： MCP1, SCYA2,CCL2
蛋白名称： MCP1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Monocyte secretory protein JE
Organism-1： Human
基因ID-1： 6347
SwissProt-1： P13500
背景： This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆号： PT0877R
特异性： Endogenous
基因名称： MCP1, SCYA2,CCL2
蛋白名称： MCP1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Monocyte secretory protein JE
Organism-1： Human
基因ID-1： 6347
SwissProt-1： P13500
背景： This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
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