储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0164R
特异性： Endogenous
基因名称： CCNE1
蛋白名称： G1/S-specific cyclin-E1
别名： CCNE1;CCNE;G1/S-specific cyclin-E1
Organism-1： Human
基因ID-1： 898
SwissProt-1： P24864
Organism-2： Mouse
基因ID-2： 12447
SwissProt-2： Q61457
Organism-3： Rat
SwissProt-3： P39949
背景： The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0164R
特异性： Endogenous
基因名称： CCNE1
蛋白名称： G1/S-specific cyclin-E1
别名： CCNE1;CCNE;G1/S-specific cyclin-E1
Organism-1： Human
基因ID-1： 898
SwissProt-1： P24864
Organism-2： Mouse
基因ID-2： 12447
SwissProt-2： Q61457
Organism-3： Rat
SwissProt-3： P39949
背景： The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in
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