储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0330R
特异性: This antibody detects endogenous levels of Histone H2A.X only when phosphorylated at Ser139.This antibody does not recognize phosphorylated at other sites.
基因名称: H2AFX
蛋白名称: Histone H2A.x
别名: H2AFX;H2AX;Histone H2A.x;H2a/x
Organism-1: Human
基因ID-1: 3014
SwissProt-1: P16104
Organism-2: Mouse
基因ID-2: 15270
SwissProt-2: P27661
背景: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0330R
特异性: This antibody detects endogenous levels of Histone H2A.X only when phosphorylated at Ser139.This antibody does not recognize phosphorylated at other sites.
基因名称: H2AFX
蛋白名称: Histone H2A.x
别名: H2AFX;H2AX;Histone H2A.x;H2a/x
Organism-1: Human
基因ID-1: 3014
SwissProt-1: P16104
Organism-2: Mouse
基因ID-2: 15270
SwissProt-2: P27661
背景: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],