xCT Rabbit mAb

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xCT Rabbit mAb

商品货号： PRM8464

适应性： 人,小鼠,大鼠

￥7000元

规格：

500ul

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说明书

商品描述

发货日期：现货
靶点-Target： SLC7A11
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 37kD
MW(Observed)： 55kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0398R
特异性： Endogenous
基因名称： SLC7A11
蛋白名称： Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
别名： Cystine/glutamate transporter;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Solute carrier family 7 member 11;xCT;
Organism-1： Human
基因ID-1： 23657
SwissProt-1： Q9UPY5
Organism-2： Mouse
基因ID-2： 26570
SwissProt-2： Q9WTR6
背景： This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
细胞定位： Membrane

xCT Rabbit mAb

Catalog No PRM8464

Product information

发货日期：现货
靶点-Target： SLC7A11
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 37kD
MW(Observed)： 55kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0398R
特异性： Endogenous
基因名称： SLC7A11
蛋白名称： Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
别名： Cystine/glutamate transporter;Amino acid transport system xc-;Calcium channel blocker resistance protein CCBR1;Solute carrier family 7 member 11;xCT;
Organism-1： Human
基因ID-1： 23657
SwissProt-1： Q9UPY5
Organism-2： Mouse
基因ID-2： 26570
SwissProt-2： Q9WTR6
背景： This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
细胞定位： Membrane

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