RPA32/RPA2 Rabbit mAb

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商品货号： PRM8453

适应性： 人,小鼠,大鼠

￥800元

规格：

50ul

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说明书

商品描述

发货日期：现货
靶点-Target： RFA2
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 29kD
MW(Observed)： 29kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0446R
特异性： Endogenous
基因名称： RPA2
蛋白名称： Replication protein A 32 kDa subunit
别名： RPA2;REPA2;RPA32;RPA34;Replication protein A 32 kDa subunit;RP-A p32;Replication factor A protein 2;RF-A protein 2;Replication protein A 34 kDa subunit;RP-A p34
Organism-1： Human
基因ID-1： 6118
SwissProt-1： P15927
Organism-2： Mouse
SwissProt-2： Q62193
Organism-3： Rat
基因ID-3： 59102
SwissProt-3： Q63528
背景： function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
细胞定位： Nucleus

RPA32/RPA2 Rabbit mAb

Catalog No PRM8453

Product information

发货日期：现货
靶点-Target： RFA2
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 29kD
MW(Observed)： 29kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0446R
特异性： Endogenous
基因名称： RPA2
蛋白名称： Replication protein A 32 kDa subunit
别名： RPA2;REPA2;RPA32;RPA34;Replication protein A 32 kDa subunit;RP-A p32;Replication factor A protein 2;RF-A protein 2;Replication protein A 34 kDa subunit;RP-A p34
Organism-1： Human
基因ID-1： 6118
SwissProt-1： P15927
Organism-2： Mouse
SwissProt-2： Q62193
Organism-3： Rat
基因ID-3： 59102
SwissProt-3： Q63528
背景： function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
细胞定位： Nucleus

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