储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0370R
特异性： Endogenous
基因名称： E2F1
蛋白名称： Transcription factor E2F1
别名： E2F1;RBBP3;Transcription factor E2F1;E2F-1;PBR3;Retinoblastoma-associated protein 1;RBAP-1;Retinoblastoma-binding protein 3;RBBP-3;pRB-binding protein E2F-1
Organism-1： Human
基因ID-1： 1869
SwissProt-1： Q01094
Organism-2： Mouse
基因ID-2： 13555
SwissProt-2： Q61501
背景： The protein encoded by this gene is a member ofThe E2F family of transcription factors.The E2F family plays a crucial role inThe control of cell cycle and action of tumor suppressor proteins and is also a target ofThe transforming proteins of small DNA tumor viruses.The E2F proteins contain several evolutionally conserved domains found in most members ofThe family. These domains include a DNA binding domain, a dimerization domain which determines interaction withThe differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded withinThe transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0370R
特异性： Endogenous
基因名称： E2F1
蛋白名称： Transcription factor E2F1
别名： E2F1;RBBP3;Transcription factor E2F1;E2F-1;PBR3;Retinoblastoma-associated protein 1;RBAP-1;Retinoblastoma-binding protein 3;RBBP-3;pRB-binding protein E2F-1
Organism-1： Human
基因ID-1： 1869
SwissProt-1： Q01094
Organism-2： Mouse
基因ID-2： 13555
SwissProt-2： Q61501
背景： The protein encoded by this gene is a member ofThe E2F family of transcription factors.The E2F family plays a crucial role inThe control of cell cycle and action of tumor suppressor proteins and is also a target ofThe transforming proteins of small DNA tumor viruses.The E2F proteins contain several evolutionally conserved domains found in most members ofThe family. These domains include a DNA binding domain, a dimerization domain which determines interaction withThe differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded withinThe transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can media
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