Cleaved Caspase-3 (Asp175) Rabbit mAb

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商品货号： PRM8319

适应性： 人,小鼠,大鼠

￥7000元

规格：

500ul

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说明书

商品描述

发货日期：现货
靶点-Target： Caspase-3
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 17kD,19kD
MW(Observed)： 17kD,19kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0457R
特异性： This antibody detects endogenous levels of Cleaved Caspase-3 (Asp175).
基因名称： CASP3
蛋白名称： Caspase3
别名： CASP3;CPP32;Caspase-3;CASP-3;Apopain;Cysteine protease CPP32;CPP-32;Protein Yama;SREBP cleavage activity 1;SCA-1
Organism-1： Human
基因ID-1： 836
SwissProt-1： P42574
Organism-2： Mouse
基因ID-2： 12367
SwissProt-2： P70677
Organism-3： Rat
基因ID-3： 25402
SwissProt-3： P55213
背景： This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
细胞定位： Cytoplasm

Cleaved Caspase-3 (Asp175) Rabbit mAb

Catalog No PRM8319

Product information

发货日期：现货
靶点-Target： Caspase-3
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 17kD,19kD
MW(Observed)： 17kD,19kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0457R
特异性： This antibody detects endogenous levels of Cleaved Caspase-3 (Asp175).
基因名称： CASP3
蛋白名称： Caspase3
别名： CASP3;CPP32;Caspase-3;CASP-3;Apopain;Cysteine protease CPP32;CPP-32;Protein Yama;SREBP cleavage activity 1;SCA-1
Organism-1： Human
基因ID-1： 836
SwissProt-1： P42574
Organism-2： Mouse
基因ID-2： 12367
SwissProt-2： P70677
Organism-3： Rat
基因ID-3： 25402
SwissProt-3： P55213
背景： This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
细胞定位： Cytoplasm

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