储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0566R
特异性： Endogenous
基因名称： CAV1
蛋白名称： Caveolin-1
别名： CAV1;CAV;Caveolin-1
Organism-1： Human
基因ID-1： 857
SwissProt-1： Q03135
Organism-2： Mouse
基因ID-2： 12389
SwissProt-2： P49817
Organism-3： Rat
SwissProt-3： P41350
背景： The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010],
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0566R
特异性： Endogenous
基因名称： CAV1
蛋白名称： Caveolin-1
别名： CAV1;CAV;Caveolin-1
Organism-1： Human
基因ID-1： 857
SwissProt-1： Q03135
Organism-2： Mouse
基因ID-2： 12389
SwissProt-2： P49817
Organism-3： Rat
SwissProt-3： P41350
背景： The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010],
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