储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0603R
特异性： Endogenous
基因名称： BCL2L11
蛋白名称： Bcl-2-like protein 11
别名： BCL2L11;BIM;Bcl-2-like protein 11;Bcl2-L-11;Bcl2-interacting mediator of cell death
Organism-1： Human
基因ID-1： 10018
SwissProt-1： O43521
Organism-2： Mouse
基因ID-2： 12125
SwissProt-2： O54918
Organism-3： Rat
基因ID-3： 64547
SwissProt-3： O88498
背景： The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013],
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0603R
特异性： Endogenous
基因名称： BCL2L11
蛋白名称： Bcl-2-like protein 11
别名： BCL2L11;BIM;Bcl-2-like protein 11;Bcl2-L-11;Bcl2-interacting mediator of cell death
Organism-1： Human
基因ID-1： 10018
SwissProt-1： O43521
Organism-2： Mouse
基因ID-2： 12125
SwissProt-2： O54918
Organism-3： Rat
基因ID-3： 64547
SwissProt-3： O88498
背景： The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013],
在线咨询
湘公网安备