储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0803R
特异性： Endogenous
基因名称： BRAT1;BAAT1;C7orf27
蛋白名称： BRCA1-associated ATM activator 1;BRCA1-associated protein required for ATM activation protein 1;
别名： BRAT1;BAAT1;C7orf27;BRCA1-associated ATM activator 1 ;BRCA1-associated protein required for ATM activation protein 1;
Organism-1： Human
基因ID-1： 221927
SwissProt-1： Q6PJG6
背景： The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
细胞定位： Nucleus. Cytoplasm. Note=Present at double strand breaks (DSBs)following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner..
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0803R
特异性： Endogenous
基因名称： BRAT1;BAAT1;C7orf27
蛋白名称： BRCA1-associated ATM activator 1;BRCA1-associated protein required for ATM activation protein 1;
别名： BRAT1;BAAT1;C7orf27;BRCA1-associated ATM activator 1 ;BRCA1-associated protein required for ATM activation protein 1;
Organism-1： Human
基因ID-1： 221927
SwissProt-1： Q6PJG6
背景： The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
细胞定位： Nucleus. Cytoplasm. Note=Present at double strand breaks (DSBs)following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner..
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