储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0632R
特异性: Endogenous
基因名称: Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
蛋白名称: Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
别名: ESR1 ESR NR3A1
Organism-1: Human
基因ID-1: 2099
SwissProt-1: P03372
Organism-2: Mouse
基因ID-2: 13982
SwissProt-2: P19785
Organism-3: Rat
基因ID-3: 24890
SwissProt-3: P06211
背景: estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0632R
特异性: Endogenous
基因名称: Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
蛋白名称: Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
别名: ESR1 ESR NR3A1
Organism-1: Human
基因ID-1: 2099
SwissProt-1: P03372
Organism-2: Mouse
基因ID-2: 13982
SwissProt-2: P19785
Organism-3: Rat
基因ID-3: 24890
SwissProt-3: P06211
背景: estrogen receptor 1(ESR1) Homo sapiens This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014],