储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0530R
特异性： Endogenous
基因名称： PYCARD
蛋白名称： Apoptosis-associated speck-like protein containing a CARD
别名： PYCARD;ASC;CARD5;TMS1;Apoptosis-associated speck-like protein containing a CARD;hASC;Caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;Target of methylation-induced silencing 1
Organism-1： Human
基因ID-1： 29108
SwissProt-1： Q9ULZ3
Organism-2： Mouse
基因ID-2： 66824
SwissProt-2： Q9EPB4
背景： This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0530R
特异性： Endogenous
基因名称： PYCARD
蛋白名称： Apoptosis-associated speck-like protein containing a CARD
别名： PYCARD;ASC;CARD5;TMS1;Apoptosis-associated speck-like protein containing a CARD;hASC;Caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;Target of methylation-induced silencing 1
Organism-1： Human
基因ID-1： 29108
SwissProt-1： Q9ULZ3
Organism-2： Mouse
基因ID-2： 66824
SwissProt-2： Q9EPB4
背景： This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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