储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0653R
特异性： Endogenous
基因名称： XIAP
蛋白名称： E3 ubiquitin-protein ligase XIAP
别名： XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I
Organism-1： Human
基因ID-1： 331
SwissProt-1： P98170
Organism-2： Mouse
基因ID-2： 11798
SwissProt-2： Q60989
Organism-3： Rat
基因ID-3： 63879
SwissProt-3： Q9R0I6
背景： This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011],
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0653R
特异性： Endogenous
基因名称： XIAP
蛋白名称： E3 ubiquitin-protein ligase XIAP
别名： XIAP;API3;BIRC4;IAP3;E3 ubiquitin-protein ligase XIAP;Baculoviral IAP repeat-containing protein 4;IAP-like protein;ILP;hILP;Inhibitor of apoptosis protein 3;IAP-3;hIAP-3;hIAP3;X-linked inhibitor of apoptosis protein;X-linked I
Organism-1： Human
基因ID-1： 331
SwissProt-1： P98170
Organism-2： Mouse
基因ID-2： 11798
SwissProt-2： Q60989
Organism-3： Rat
基因ID-3： 63879
SwissProt-3： Q9R0I6
背景： This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011],
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