储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0583R
特异性： Endogenous
基因名称： CANX
蛋白名称： Calnexin
别名： CANX;Calnexin;IP90;Major histocompatibility complex class I antigen-binding protein p88;p90
Organism-1： Human
基因ID-1： 821
SwissProt-1： P27824
Organism-2： Mouse
基因ID-2： 12330
SwissProt-2： P35564
Organism-3： Rat
基因ID-3： 29144
SwissProt-3： P35565
背景： This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
细胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0583R
特异性： Endogenous
基因名称： CANX
蛋白名称： Calnexin
别名： CANX;Calnexin;IP90;Major histocompatibility complex class I antigen-binding protein p88;p90
Organism-1： Human
基因ID-1： 821
SwissProt-1： P27824
Organism-2： Mouse
基因ID-2： 12330
SwissProt-2： P35564
Organism-3： Rat
基因ID-3： 29144
SwissProt-3： P35565
背景： This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
细胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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