Androgen Receptor Rabbit mAb

> > >

商品货号： PRM8067

适应性： 人,小鼠,大鼠

￥800元

规格：

50ul

在线咨询

MSDS

说明书

商品描述

发货日期：现货
靶点-Target： Androgen Receptor
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 99kD
MW(Observed)： 110kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0833R
特异性： Endogenous
基因名称： AR DHTR NR3C4
蛋白名称： AR
别名： Androgen receptor;Dihydrotestosterone receptor;Nuclear receptor subfamily 3 group C member 4;
Organism-1： Human
基因ID-1： 367
SwissProt-1： P10275
背景： The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoform
细胞定位： Nuclear

Androgen Receptor Rabbit mAb

Catalog No PRM8067

Product information

发货日期：现货
靶点-Target： Androgen Receptor
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IHC,IF,IP,ELISA
MW(Calculated)： 99kD
MW(Observed)： 110kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Unmodified
推荐稀释比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0833R
特异性： Endogenous
基因名称： AR DHTR NR3C4
蛋白名称： AR
别名： Androgen receptor;Dihydrotestosterone receptor;Nuclear receptor subfamily 3 group C member 4;
Organism-1： Human
基因ID-1： 367
SwissProt-1： P10275
背景： The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoform
细胞定位： Nuclear

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.