储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0852R
特异性： Endogenous
基因名称： MAPK9
蛋白名称： Mitogen-activated protein kinase 9
别名： MAPK9;JNK2;PRKM9;SAPK1A;Mitogen-activated protein kinase 9;MAP kinase 9;MAPK 9;JNK-55;Stress-activated protein kinase 1a;SAPK1a;Stress-activated protein kinase JNK2;c-Jun N-terminal kinase 2
Organism-1： Human
基因ID-1： 5601
SwissProt-1： P45984
Organism-2： Mouse
基因ID-2： 26420
SwissProt-2： Q9WTU6
Organism-3： Rat
基因ID-3： 50658
SwissProt-3： P49186
背景： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternative
细胞定位： Cytoplasm . Nucleus . Colocalizes with POU5F1 in the nucleus. .
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0852R
特异性： Endogenous
基因名称： MAPK9
蛋白名称： Mitogen-activated protein kinase 9
别名： MAPK9;JNK2;PRKM9;SAPK1A;Mitogen-activated protein kinase 9;MAP kinase 9;MAPK 9;JNK-55;Stress-activated protein kinase 1a;SAPK1a;Stress-activated protein kinase JNK2;c-Jun N-terminal kinase 2
Organism-1： Human
基因ID-1： 5601
SwissProt-1： P45984
Organism-2： Mouse
基因ID-2： 26420
SwissProt-2： Q9WTU6
Organism-3： Rat
基因ID-3： 50658
SwissProt-3： P49186
背景： The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternative
细胞定位： Cytoplasm . Nucleus . Colocalizes with POU5F1 in the nucleus. .
在线咨询
湘公网安备