IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb

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商品货号： PRM8007

适应性： 人,小鼠,大鼠

￥7000元

规格：

500ul

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说明书

商品描述

发货日期：现货
靶点-Target： IGF IR
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 156kD
MW(Observed)： 95kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Phospho
修饰-Modification： Tyr1135/1136/Tyr1150/1151
推荐稀释比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0867R
特异性： Antibody detects endogenous levels of IGF-I receptor and insulin receptor only when phosphorylated at tyrosine 1135/1136 or tyrosine 1150/1151, respectively. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): MAyLN
基因名称： IGF1R
蛋白名称： Insulin-like growth factor 1 receptor
别名： IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
Organism-1： Human
基因ID-1： 3480;3643
SwissProt-1： P06213;P08069
Organism-2： Mouse
基因ID-2： 16001;16337
Organism-3： Rat
基因ID-3： 25718
SwissProt-3： P24062;P15127
背景： This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位： Cell membrane ; Single-pass type I membrane protein .

IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb

Catalog No PRM8007

Product information

发货日期：现货
靶点-Target： IGF IR
反应性-Reactivity：人,小鼠,大鼠
应用-Applications： WB,IF,IP,ELISA
MW(Calculated)： 156kD
MW(Observed)： 95kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
偶联-Conjugate： Phospho
修饰-Modification： Tyr1135/1136/Tyr1150/1151
推荐稀释比： WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0867R
特异性： Antibody detects endogenous levels of IGF-I receptor and insulin receptor only when phosphorylated at tyrosine 1135/1136 or tyrosine 1150/1151, respectively. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): MAyLN
基因名称： IGF1R
蛋白名称： Insulin-like growth factor 1 receptor
别名： IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
Organism-1： Human
基因ID-1： 3480;3643
SwissProt-1： P06213;P08069
Organism-2： Mouse
基因ID-2： 16001;16337
Organism-3： Rat
基因ID-3： 25718
SwissProt-3： P24062;P15127
背景： This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位： Cell membrane ; Single-pass type I membrane protein .

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