储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0680R
特异性: This antibody detects endogenous levels of Cleaved N-terminal GSDMD.
基因名称: GSDMD
蛋白名称: Gasdermin domain-containing protein 1,Gasdermin-D,GSDMD,GSDMD-CT,GSDMD-NT,GSDMD_人
Organism-1: 人
SwissProt-1: P57764
细胞定位: [Gasdermin-D]: Cytoplasm, cytosol . Inflammasome . In response to a canonical inflammasome stimulus, such as nigericin, recruited to NLRP3 inflammasone with similar kinetics to that of uncleaved CASP1 precursor. .; [Gasdermin-D, N-terminal]: Cell membrane ; Multi-pass membrane protein . Secreted . Released in the extracellular milieu following pyroptosis. .; [Gasdermin-D, C-terminal]: Cytoplasm, cytosol .
组织表达: Expressed in the suprabasal cells of esophagus, as well as in the isthmus/neck, pit, and gland of the stomach, suggesting preferential expression in differentiating cells.
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆号: PT0680R
特异性: This antibody detects endogenous levels of Cleaved N-terminal GSDMD.
基因名称: GSDMD
蛋白名称: Gasdermin domain-containing protein 1,Gasdermin-D,GSDMD,GSDMD-CT,GSDMD-NT,GSDMD_人
Organism-1: 人
SwissProt-1: P57764
细胞定位: [Gasdermin-D]: Cytoplasm, cytosol . Inflammasome . In response to a canonical inflammasome stimulus, such as nigericin, recruited to NLRP3 inflammasone with similar kinetics to that of uncleaved CASP1 precursor. .; [Gasdermin-D, N-terminal]: Cell membrane ; Multi-pass membrane protein . Secreted . Released in the extracellular milieu following pyroptosis. .; [Gasdermin-D, C-terminal]: Cytoplasm, cytosol .
组织表达: Expressed in the suprabasal cells of esophagus, as well as in the isthmus/neck, pit, and gland of the stomach, suggesting preferential expression in differentiating cells.