ADAM10 (PT0709R) PT® Rabbit mAb

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商品货号： PLR10002

适应性： 人,小鼠,大鼠

￥1200元

规格：

100μL

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商品描述

靶点-Target： ADAM10
MW(Calculated)： 84kD
MW(Observed)： 84kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
修饰-Modification： Unmodified
推荐稀释比： IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0709R
特异性： Endogenous
基因名称： ADAM10
蛋白名称： Disintegrin and metalloproteinase domain-containing protein 10
别名： ADAM10;KUZ;MADM;Disintegrin and metalloproteinase domain-containing protein 10;ADAM 10;CDw156;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;CD156c
Organism-1：人
基因ID-1： 102
SwissProt-1： O14672
Organism-2： Mouse
基因ID-2： 11487
SwissProt-2： O35598
Organism-3： Rat
SwissProt-3： Q10743
细胞定位： Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011). .
组织表达： Expressed in the brain (at protein level) (PubMed:23676497). Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver (PubMed:11511685, PubMed:9016778).

ADAM10 (PT0709R) PT® Rabbit mAb

Catalog No PLR10002

Product information

靶点-Target： ADAM10
MW(Calculated)： 84kD
MW(Observed)： 84kD
宿主物种-Host Species： Rabbit
同种型-Isotype： IgG,Kappa
修饰-Modification： Unmodified
推荐稀释比： IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺： Protein A
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性： Monoclonal
克隆号： PT0709R
特异性： Endogenous
基因名称： ADAM10
蛋白名称： Disintegrin and metalloproteinase domain-containing protein 10
别名： ADAM10;KUZ;MADM;Disintegrin and metalloproteinase domain-containing protein 10;ADAM 10;CDw156;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;CD156c
Organism-1：人
基因ID-1： 102
SwissProt-1： O14672
Organism-2： Mouse
基因ID-2： 11487
SwissProt-2： O35598
Organism-3： Rat
SwissProt-3： Q10743
细胞定位： Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011). .
组织表达： Expressed in the brain (at protein level) (PubMed:23676497). Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver (PubMed:11511685, PubMed:9016778).

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