其他名称： PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)
分子量： 146kD
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by autophosphorylation on Thr-1161 and Thr-1165 and inhibited by the first PAS domain.,PTM:Autophosphorylated on Thr-1161 and Thr-1165.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,tissue specificity:Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta.,
细胞定位： Cytoplasm . Nucleus . Localizes in the nucleus of testis germ cells and in the midpiece of sperm tails.
组织表达： Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta. Present in germ cells of testis and in the midpiece of sperm tails (at protein level).
其他名称： PAS domain-containing serine/threonine-protein kinase (PAS-kinase) (PASKIN) (hPASK) (EC 2.7.11.1)
分子量： 146kD
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by autophosphorylation on Thr-1161 and Thr-1165 and inhibited by the first PAS domain.,PTM:Autophosphorylated on Thr-1161 and Thr-1165.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,tissue specificity:Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta.,
细胞定位： Cytoplasm . Nucleus . Localizes in the nucleus of testis germ cells and in the midpiece of sperm tails.
组织表达： Ubiquitously expressed, with slightly higher expression in brain, prostate and testis. Reduced expression was found in placenta. Present in germ cells of testis and in the midpiece of sperm tails (at protein level).
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