其他名称： 14-3-3 protein sigma (Epithelial cell marker protein 1;Stratifin)
实测条带： 30kD
功能： function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
相关产品： RS0001,RS0002,YM3028,YM3279
细胞定位： Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.
组织表达： Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
其他名称： 14-3-3 protein sigma (Epithelial cell marker protein 1;Stratifin)
实测条带： 30kD
功能： function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.,function:p53-regulated inhibitor of G2/M progression.,similarity:Belongs to the 14-3-3 family.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Homodimer. Interacts with KRT17 (By similarity). Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN.,tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.,
相关产品： RS0001,RS0002,YM3028,YM3279
细胞定位： Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.
组织表达： Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
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