PDGF Receptor β (Phospho Tyr1009) rabbit pAb

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商品货号： PLP001406

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： PDGFRB PDGFR PDGFR1
蛋白名称： Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Human_gene_id： 5159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5159
Human_swiss_prot_no： P09619
Human_swiss_link： https://www.uniprot.org/uniprotkb/P09619/entry
Mouse_gene_id： 18596
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18596
Mouse_swiss_prot_no： P05622
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P05622/entry
Rat_gene_id： 24629
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24629
Rat_swiss_prot_no： Q05030
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q05030/entry
特异性： This antibody detects endogenous levels of Human Mouse PDGF Receptor β (phospho-Tyr1009)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
实测条带： 135-180kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;Calcium;Cytokine-cytokine receptor interaction;Endocytosis;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Colorectal cancer;Glioma;Prostate cancer;Melanoma;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:A fusion of PDGFRA and FIP1L1 (FIP1L1-PDGFRA), due to an interstitial chromosomal deletion, is the cause of some cases of hypereosinophilic syndrome (HES) [MIM:607685]. HES is a rare hematologic disorder characterized by sustained overproduction of eosinophils in the bone marrow, eosinophilia, tissue infiltration and organ damage.,function:Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Homodimer, and heterodimer with PDGFRB. Interacts with the SH2 domain of SHB via phosphorylated Tyr-720 (By similarity). Interacts with the SH2 domain of SHF via phosphorylated Tyr-720.,tissue specificity:Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue.,
相关产品： YT6139,YT5265,YT3636,YT3635,YT3634,YT3633,YT3632,YP0993,YP0992,YP0441,YM3688,YM3687,KA4225C,KA3358C,KA1725C,KA1321C
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus .
组织表达： Detected in platelets (at protein level). Widely expressed. Detected in brain, fibroblasts, smooth muscle, heart, and embryo. Expressed in primary and metastatic colon tumors and in normal colon tissue.
科研货号： PLP001406

PDGF Receptor β (Phospho Tyr1009) rabbit pAb

Catalog No PLP001406

Product information

基因名称： PDGFRB PDGFR PDGFR1
蛋白名称： Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Human_gene_id： 5159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5159
Human_swiss_prot_no： P09619
Human_swiss_link： https://www.uniprot.org/uniprotkb/P09619/entry
Mouse_gene_id： 18596
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18596
Mouse_swiss_prot_no： P05622
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P05622/entry
Rat_gene_id： 24629
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24629
Rat_swiss_prot_no： Q05030
Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q05030/entry
特异性： This antibody detects endogenous levels of Human Mouse PDGF Receptor β (phospho-Tyr1009)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PDGFRB; PDGFR; PDGFR1; Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; Platelet-deri
实测条带： 135-180kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;Calcium;Cytokine-cytokine receptor interaction;Endocytosis;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Colorectal cancer;Glioma;Prostate cancer;Melanoma;
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:A fusion of PDGFRA and FIP1L1 (FIP1L1-PDGFRA), due to an interstitial chromosomal deletion, is the cause of some cases of hypereosinophilic syndrome (HES) [MIM:607685]. HES is a rare hematologic disorder characterized by sustained overproduction of eosinophils in the bone marrow, eosinophilia, tissue infiltration and organ damage.,function:Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Homodimer, and heterodimer with PDGFRB. Interacts with the SH2 domain of SHB via phosphorylated Tyr-720 (By similarity). Interacts with the SH2 domain of SHF via phosphorylated Tyr-720.,tissue specificity:Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue.,
相关产品： YT6139,YT5265,YT3636,YT3635,YT3634,YT3633,YT3632,YP0993,YP0992,YP0441,YM3688,YM3687,KA4225C,KA3358C,KA1725C,KA1321C
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus .
组织表达： Detected in platelets (at protein level). Widely expressed. Detected in brain, fibroblasts, smooth muscle, heart, and embryo. Expressed in primary and metastatic colon tumors and in normal colon tissue.
科研货号： PLP001406

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