MCM2 (Phospho Ser139) rabbit pAb

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商品货号： PLP001375

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MCM2 BM28 CCNL1 CDCL1 KIAA0030
蛋白名称： MCM2 (Ser139)
Human_gene_id： 4171
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4171
Human_swiss_prot_no： P49736
Human_swiss_link： https://www.uniprot.org/uniprotkb/P49736/entry
Mouse_gene_id： 17216
Mouse_gene_link： https://www.uniprot.org/uniprot/17216
Mouse_swiss_prot_no： P97310
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P97310
特异性： This antibody detects endogenous levels of Human Mouse Rat MCM2 (phospho-Ser139)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
实测条带： 120kD
信号通路： DNA replication;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： function:Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.,PTM:Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,subunit:Interacts with DBF4 (By similarity). Interacts with MYST2. May interact with MCM10.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .
组织表达： Bone marrow,Brain,Cervix carcinoma,Colon carcinoma,Epitheli
科研货号： PLP001375

MCM2 (Phospho Ser139) rabbit pAb

Catalog No PLP001375

Product information

基因名称： MCM2 BM28 CCNL1 CDCL1 KIAA0030
蛋白名称： MCM2 (Ser139)
Human_gene_id： 4171
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4171
Human_swiss_prot_no： P49736
Human_swiss_link： https://www.uniprot.org/uniprotkb/P49736/entry
Mouse_gene_id： 17216
Mouse_gene_link： https://www.uniprot.org/uniprot/17216
Mouse_swiss_prot_no： P97310
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P97310
特异性： This antibody detects endogenous levels of Human Mouse Rat MCM2 (phospho-Ser139)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
实测条带： 120kD
信号通路： DNA replication;Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： function:Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.,PTM:Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the MCM family.,similarity:Contains 1 MCM domain.,subunit:Interacts with DBF4 (By similarity). Interacts with MYST2. May interact with MCM10.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .
组织表达： Bone marrow,Brain,Cervix carcinoma,Colon carcinoma,Epitheli
科研货号： PLP001375

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