IGF2R (Phospho Ser2484) Polyclonal Antibody

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商品货号： PLP001230

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： IGF2R MPRI
蛋白名称： IGF2R (Phospho-Ser2484)
Human_gene_id： 3482
Human_swiss_prot_no： P11717
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11717/entry
Rat_swiss_link： Human:S2484, Mouse:S2476, Rat:S2472
特异性： This antibody detects endogenous phospho levels of IGF2R (Phospho-Ser2484) at Human:S2484, Mouse:S2476, Rat:S2472
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor;CI-MPR;M6PR;300 kDa mannose 6-phosphate receptor;MPR 300;Insulin-like growth factor 2 receptor;Insulin-like growth factor II receptor;IGF-II receptor;M6P/IGF2 receptor;M6P/IGF2R;CD antigen CD222)
实测条带： 300kD
功能： domain:Contains 15 repeating units of approximately 147 AA. The most highly conserved region within the repeat consists of a stretch of 13 AA that contains cysteines at both ends.,function:Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.,similarity:Belongs to the MRL1/IGF2R family.,similarity:Contains 1 fibronectin type-II domain.,subunit:Binds GGA1, GGA2 and GGA3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Mainly localized in the Golgi at steady state and not detectable in lysosome (PubMed:18817523). Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005). .
组织表达： Brain,Epithelium,Liver,
科研货号： PLP001230

IGF2R (Phospho Ser2484) Polyclonal Antibody

Catalog No PLP001230

Product information

基因名称： IGF2R MPRI
蛋白名称： IGF2R (Phospho-Ser2484)
Human_gene_id： 3482
Human_swiss_prot_no： P11717
Human_swiss_link： https://www.uniprot.org/uniprotkb/P11717/entry
Rat_swiss_link： Human:S2484, Mouse:S2476, Rat:S2472
特异性： This antibody detects endogenous phospho levels of IGF2R (Phospho-Ser2484) at Human:S2484, Mouse:S2476, Rat:S2472
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC-p 1:50-200, WB 1:500-2000. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor;CI-MPR;M6PR;300 kDa mannose 6-phosphate receptor;MPR 300;Insulin-like growth factor 2 receptor;Insulin-like growth factor II receptor;IGF-II receptor;M6P/IGF2 receptor;M6P/IGF2R;CD antigen CD222)
实测条带： 300kD
功能： domain:Contains 15 repeating units of approximately 147 AA. The most highly conserved region within the repeat consists of a stretch of 13 AA that contains cysteines at both ends.,function:Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.,similarity:Belongs to the MRL1/IGF2R family.,similarity:Contains 1 fibronectin type-II domain.,subunit:Binds GGA1, GGA2 and GGA3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus membrane ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Mainly localized in the Golgi at steady state and not detectable in lysosome (PubMed:18817523). Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005). .
组织表达： Brain,Epithelium,Liver,
科研货号： PLP001230

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