Sodium Potassium ATPase alpha-1 (Phospho Tyr260) Antibody

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商品货号： PLP001204

适应性： 人,大鼠,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ATP1A1
蛋白名称： Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)
Human_gene_id： 476
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=476
Human_swiss_prot_no： P05023
Human_swiss_link： http://www.uniprot.org/uniprotkb/P05023/entry
Mouse_swiss_prot_no： Q8VDN2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8VDN2
Rat_swiss_prot_no： P06685
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P06685
特异性： The antibody detects endogenous Sodium Potassium ATPase alpha-1 when Phospho occurs at Tyr260)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)
实测条带： 115kD
信号通路： Cardiac muscle contraction;Aldosterone-regulated sodium reabsorption;
功能： catalytic activity:ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).,function:This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.,PTM:Phosphorylation on Tyr-10 modulates pumping activity.,similarity:Belongs to the cation transport ATPase (P-type) family.,similarity:Belongs to the cation transport ATPase (P-type) family. Type IIC subfamily.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma. Binds the HLA class II histocompatibility antigen, DR1.,
相关产品： YT6164,YT2973,YT2971,YP1226,YP1212,YP0644,KA4381C,KA3036C,KA1027C
细胞定位： Basolateral cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell projection, axon . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
组织表达： Brain,Cerebellum,Cervix,Placenta,Retinal pigment epithelium
科研货号： PLP001204

Sodium Potassium ATPase alpha-1 (Phospho Tyr260) Antibody

Catalog No PLP001204

Product information

基因名称： ATP1A1
蛋白名称： Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)
Human_gene_id： 476
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=476
Human_swiss_prot_no： P05023
Human_swiss_link： http://www.uniprot.org/uniprotkb/P05023/entry
Mouse_swiss_prot_no： Q8VDN2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8VDN2
Rat_swiss_prot_no： P06685
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P06685
特异性： The antibody detects endogenous Sodium Potassium ATPase alpha-1 when Phospho occurs at Tyr260)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)
实测条带： 115kD
信号通路： Cardiac muscle contraction;Aldosterone-regulated sodium reabsorption;
功能： catalytic activity:ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).,function:This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.,PTM:Phosphorylation on Tyr-10 modulates pumping activity.,similarity:Belongs to the cation transport ATPase (P-type) family.,similarity:Belongs to the cation transport ATPase (P-type) family. Type IIC subfamily.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Composed of three subunits: alpha (catalytic), beta and gamma. Binds the HLA class II histocompatibility antigen, DR1.,
相关产品： YT6164,YT2973,YT2971,YP1226,YP1212,YP0644,KA4381C,KA3036C,KA1027C
细胞定位： Basolateral cell membrane ; Multi-pass membrane protein . Cell membrane, sarcolemma ; Multi-pass membrane protein . Cell projection, axon . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
组织表达： Brain,Cerebellum,Cervix,Placenta,Retinal pigment epithelium
科研货号： PLP001204

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