MER/TYRO3 (Phospho Tyr753/Tyr685) Polyclonal Antibody

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商品货号： PLP001200

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MERTK MER
蛋白名称： c-mer proto-oncogene tyrosine kinase
Human_gene_id： 10461/7301
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10461
Human_swiss_prot_no： Q12866/Q06418
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q12866/entry
特异性： This antibody detects endogenous levels of MER/TYRO3 at Human:Y753/Y685;Mouse:Y748/Y675;Rat:Y748/Y675, It doesn't reacte with total protein.
组成： PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MERTK MER
实测条带： 110kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in MERTK are a cause of retinitis pigmentosa (RP) [MIM:268000]. RP that leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.,function:In case of filovirus infection, seems to function as a cell entry factor.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein .
组织表达： Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Highly expressed in testis, ovary, prostate, lung, and kidney, with lower expression in spleen, small intestine, colon, and liver.
科研货号： PLP001200

MER/TYRO3 (Phospho Tyr753/Tyr685) Polyclonal Antibody

Catalog No PLP001200

Product information

基因名称： MERTK MER
蛋白名称： c-mer proto-oncogene tyrosine kinase
Human_gene_id： 10461/7301
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10461
Human_swiss_prot_no： Q12866/Q06418
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q12866/entry
特异性： This antibody detects endogenous levels of MER/TYRO3 at Human:Y753/Y685;Mouse:Y748/Y675;Rat:Y748/Y675, It doesn't reacte with total protein.
组成： PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MERTK MER
实测条带： 110kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in MERTK are a cause of retinitis pigmentosa (RP) [MIM:268000]. RP that leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.,function:In case of filovirus infection, seems to function as a cell entry factor.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein .
组织表达： Not expressed in normal B- and T-lymphocytes but is expressed in numerous neoplastic B- and T-cell lines. Highly expressed in testis, ovary, prostate, lung, and kidney, with lower expression in spleen, small intestine, colon, and liver.
科研货号： PLP001200

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