其他名称: MAX; BHLHD4; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X
分子量: 18kD
信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Pathways in cancer;Small cell lung cancer;
功能: alternative products:Additional isoforms seem to exist,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity.,PTM:Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MYC or MAD. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with SPAG9.,tissue specificity:High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Cell projection, dendrite .
组织表达: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
其他名称: MAX; BHLHD4; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X
分子量: 18kD
信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Pathways in cancer;Small cell lung cancer;
功能: alternative products:Additional isoforms seem to exist,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3-K9 histone methyltransferase activity.,PTM:Reversible lysine acetylation might regulate the nuclear-cytoplasmic shuttling of specific Max complexes.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MYC or MAD. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with SPAG9.,tissue specificity:High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Cell projection, dendrite .
组织表达: High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.