p57 (phospho Thr310) Polyclonal Antibody

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商品货号： PLP000921

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CDKN1C
蛋白名称： Cyclin-dependent kinase inhibitor 1C
Human_gene_id： 1028
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
Human_swiss_prot_no： P49918
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49918/entry
Mouse_gene_id： 12577
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12577
Mouse_swiss_prot_no： P49919
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49919
特异性： Phospho-p57 (T310) Polyclonal Antibody detects endogenous levels of p57 protein only when phosphorylated at T310.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
实测条带： 32kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
科研货号： PLP000921

p57 (phospho Thr310) Polyclonal Antibody

Catalog No PLP000921

Product information

基因名称： CDKN1C
蛋白名称： Cyclin-dependent kinase inhibitor 1C
Human_gene_id： 1028
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1028
Human_swiss_prot_no： P49918
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49918/entry
Mouse_gene_id： 12577
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12577
Mouse_swiss_prot_no： P49919
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49919
特异性： Phospho-p57 (T310) Polyclonal Antibody detects endogenous levels of p57 protein only when phosphorylated at T310.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
实测条带： 32kD
信号通路： Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;
功能： disease:Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.,disease:Defects in CDKN1C are involved in tumor formation.,function:Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver.
科研货号： PLP000921

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