Vav3 (phospho Tyr173) Polyclonal Antibody

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商品货号： PLP000834

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： VAV3
蛋白名称： Guanine nucleotide exchange factor VAV3
Human_gene_id： 10451
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10451
Human_swiss_prot_no： Q9UKW4
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UKW4/entry
Mouse_gene_id： 57257
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57257
Mouse_swiss_prot_no： Q9R0C8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9R0C8
特异性： Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
实测条带： 100kD
信号通路： Regulation of Actin Dynamics; AMPK
功能： function:Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with the PH domain of APS.,
相关产品： YT4865,YP0839,KA4318C,RS0001,RS0002,YM3028,YM3029
细胞定位： intracellular,cytosol,plasma membrane,extracellular exosome,
组织表达： Isoform 1 and isoform 3 are widely expressed; both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord; in these tissues, isoform 1 is readily detectable.
科研货号： PLP000834

Vav3 (phospho Tyr173) Polyclonal Antibody

Catalog No PLP000834

Product information

基因名称： VAV3
蛋白名称： Guanine nucleotide exchange factor VAV3
Human_gene_id： 10451
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10451
Human_swiss_prot_no： Q9UKW4
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9UKW4/entry
Mouse_gene_id： 57257
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57257
Mouse_swiss_prot_no： Q9R0C8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9R0C8
特异性： Phospho-Vav3 (Y173) Polyclonal Antibody detects endogenous levels of Vav3 protein only when phosphorylated at Y173.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
实测条带： 100kD
信号通路： Regulation of Actin Dynamics; AMPK
功能： function:Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with the PH domain of APS.,
相关产品： YT4865,YP0839,KA4318C,RS0001,RS0002,YM3028,YM3029
细胞定位： intracellular,cytosol,plasma membrane,extracellular exosome,
组织表达： Isoform 1 and isoform 3 are widely expressed; both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord; in these tissues, isoform 1 is readily detectable.
科研货号： PLP000834

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