NUDC (phospho Ser326) Polyclonal Antibody

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商品货号： PLP000821

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NUDC
蛋白名称： Nuclear migration protein nudC
Human_gene_id： 10726
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10726
Human_swiss_prot_no： Q9Y266
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y266/entry
Mouse_gene_id： 18221
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18221
Mouse_swiss_prot_no： O35685
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35685
Rat_gene_id： 29648
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29648
Rat_swiss_prot_no： Q63525
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63525
特异性： Phospho-NUDC (S326) Polyclonal Antibody detects endogenous levels of NUDC protein only when phosphorylated at S326.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NUDC; Nuclear migration protein nudC; Nuclear distribution protein C homolog
实测条带： 45kD
功能： function:Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.,induction:Up-regulated in actively dividing hematopoietic precursor cells. Up-regulated in cultured erythroleukemia TF-1 cells by granulocyte-macrophage colony-stimulating factor. Strongly down-regulated during maturation of erythroid precursor cells.,PTM:Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.,similarity:Belongs to the nudC family.,similarity:Contains 1 CS domain.,subcellular location:In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.,subunit:Binds PLK1. Binds PAFAH1B1 (By similarity). Part of a complex containing PLK1, NUDC, dynein and dynactin.,tissue specificity:Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton. Nucleus . Cytoplasm, cytoskeleton, spindle . Midbody . In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526). .
组织表达： Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
科研货号： PLP000821

NUDC (phospho Ser326) Polyclonal Antibody

Catalog No PLP000821

Product information

基因名称： NUDC
蛋白名称： Nuclear migration protein nudC
Human_gene_id： 10726
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10726
Human_swiss_prot_no： Q9Y266
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9Y266/entry
Mouse_gene_id： 18221
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18221
Mouse_swiss_prot_no： O35685
Mouse_swiss_link： http://www.uniprot.org/uniprot/O35685
Rat_gene_id： 29648
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29648
Rat_swiss_prot_no： Q63525
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63525
特异性： Phospho-NUDC (S326) Polyclonal Antibody detects endogenous levels of NUDC protein only when phosphorylated at S326.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NUDC; Nuclear migration protein nudC; Nuclear distribution protein C homolog
实测条带： 45kD
功能： function:Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.,induction:Up-regulated in actively dividing hematopoietic precursor cells. Up-regulated in cultured erythroleukemia TF-1 cells by granulocyte-macrophage colony-stimulating factor. Strongly down-regulated during maturation of erythroid precursor cells.,PTM:Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Phosphorylated by PLK and other kinases.,similarity:Belongs to the nudC family.,similarity:Contains 1 CS domain.,subcellular location:In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern.,subunit:Binds PLK1. Binds PAFAH1B1 (By similarity). Part of a complex containing PLK1, NUDC, dynein and dynactin.,tissue specificity:Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton. Nucleus . Cytoplasm, cytoskeleton, spindle . Midbody . In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526). .
组织表达： Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
科研货号： PLP000821

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