Bmx (phospho Tyr566) Polyclonal Antibody

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商品货号： PLP000712

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： BMX
蛋白名称： Cytoplasmic tyrosine-protein kinase BMX
Human_gene_id： 660
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=660
Human_swiss_prot_no： P51813
Human_swiss_link： http://www.uniprot.org/uniprotkb/P51813/entry
Mouse_gene_id： 12169
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12169
Mouse_swiss_prot_no： P97504
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97504
特异性： Phospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
实测条带： 78kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,cofactor:Binds 1 zinc ion per subunit.,domain:SH2 domain mediates interaction with RUFY1.,function:Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.,induction:Activated by IL-6 through phosphatidylinositol 3-kinase (PI3-kinase) pathway. It is likely that activation occurs through binding of phosphoinositides to the PH domain.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with RUFY1 and RUFY2.,tissue specificity:Preferentially expressed in epithelial and endothelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.
组织表达： Highly expressed in cells with great migratory potential, including endothelial cells and metastatic carcinoma cell lines.
科研货号： PLP000712

Bmx (phospho Tyr566) Polyclonal Antibody

Catalog No PLP000712

Product information

基因名称： BMX
蛋白名称： Cytoplasmic tyrosine-protein kinase BMX
Human_gene_id： 660
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=660
Human_swiss_prot_no： P51813
Human_swiss_link： http://www.uniprot.org/uniprotkb/P51813/entry
Mouse_gene_id： 12169
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12169
Mouse_swiss_prot_no： P97504
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97504
特异性： Phospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38
实测条带： 78kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,cofactor:Binds 1 zinc ion per subunit.,domain:SH2 domain mediates interaction with RUFY1.,function:Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.,induction:Activated by IL-6 through phosphatidylinositol 3-kinase (PI3-kinase) pathway. It is likely that activation occurs through binding of phosphoinositides to the PH domain.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with RUFY1 and RUFY2.,tissue specificity:Preferentially expressed in epithelial and endothelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.
组织表达： Highly expressed in cells with great migratory potential, including endothelial cells and metastatic carcinoma cell lines.
科研货号： PLP000712

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