YAP (phospho Ser127) Polyclonal Antibody

> > > >

商品货号： PLP000703

适应性： 人,小鼠,大鼠,猴

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： YAP1
蛋白名称： Yorkie homolog
Human_gene_id： 10413
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10413
Human_swiss_prot_no： P46937
Human_swiss_link： http://www.uniprot.org/uniprotkb/P46937/entry
Mouse_gene_id： 22601
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22601
Mouse_swiss_prot_no： P46938
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46938
Rat_gene_id： 363014
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=363014
Rat_swiss_prot_no： Q2EJA0
Rat_swiss_link： http://www.uniprot.org/uniprot/Q2EJA0
特异性： Phospho-YAP (S127) Polyclonal Antibody detects endogenous levels of YAP protein only when phosphorylated at S127.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
实测条带： 65kD
功能： PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif.,
相关产品： YT4924,YT4923,YP0708,KA3612C,KA1392C
细胞定位： Cytoplasm . Nucleus . Both phosphorylation and cell density can regulate its subcellular localization (PubMed:18158288, PubMed:20048001). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (PubMed:18158288, PubMed:20048001). At low density, predominantly nuclear and is translocated to the cytoplasm at high density (PubMed:18158288, PubMed:20048001, PubMed:25849865). PTPN14 induces translocation from the nucleus to the cytoplasm (PubMed:22525271). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .
组织表达： Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
科研货号： PLP000703

YAP (phospho Ser127) Polyclonal Antibody

Catalog No PLP000703

Product information

基因名称： YAP1
蛋白名称： Yorkie homolog
Human_gene_id： 10413
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10413
Human_swiss_prot_no： P46937
Human_swiss_link： http://www.uniprot.org/uniprotkb/P46937/entry
Mouse_gene_id： 22601
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22601
Mouse_swiss_prot_no： P46938
Mouse_swiss_link： http://www.uniprot.org/uniprot/P46938
Rat_gene_id： 363014
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=363014
Rat_swiss_prot_no： Q2EJA0
Rat_swiss_link： http://www.uniprot.org/uniprot/Q2EJA0
特异性： Phospho-YAP (S127) Polyclonal Antibody detects endogenous levels of YAP protein only when phosphorylated at S127.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
实测条带： 65kD
功能： PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif.,
相关产品： YT4924,YT4923,YP0708,KA3612C,KA1392C
细胞定位： Cytoplasm . Nucleus . Both phosphorylation and cell density can regulate its subcellular localization (PubMed:18158288, PubMed:20048001). Phosphorylation sequesters it in the cytoplasm by inhibiting its translocation into the nucleus (PubMed:18158288, PubMed:20048001). At low density, predominantly nuclear and is translocated to the cytoplasm at high density (PubMed:18158288, PubMed:20048001, PubMed:25849865). PTPN14 induces translocation from the nucleus to the cytoplasm (PubMed:22525271). Localized mainly to the nucleus in the early stages of embryo development with expression becoming evident in the cytoplasm at the blastocyst and epiblast stages (By similarity). .
组织表达： Increased expression seen in some liver and prostate cancers. Isoforms lacking the transactivation domain found in striatal neurons of patients with Huntington disease (at protein level).
科研货号： PLP000703

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.