Synaptotagmin 1/2 (phospho Ser309/306) Polyclonal Antibody

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商品货号： PLP000581

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SYT1/SYT2
蛋白名称： Synaptotagmin-1/2
Human_gene_id： 6857/127833
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6857
Human_swiss_prot_no： P21579/Q8N9I0
Human_swiss_link： http://www.uniprot.org/uniprotkb/P21579/entry
Mouse_gene_id： 20979/20980
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20979
Rat_gene_id： 25716/24805
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25716
Rat_swiss_prot_no： P21707/P29101
Rat_swiss_link： http://www.uniprot.org/uniprot/P21707
特异性： Phospho-Synaptotagmin 1/2 (S309/306) Polyclonal Antibody detects endogenous levels of Synaptotagmin 1/2 protein only when phosphorylated at S309/306.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT2; Synaptotagmin-2; Synaptotagmin II; SytII
实测条带： 47kD
功能： cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain mediates interaction with SV2A and STN2.,function:May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subcellular location:Synaptic vesicles and chromaffin granules.,subunit:Homotetramer (Probable). Interacts with SCAMP5, STN2, SV2A, SV2B, SV2C and RIMS1. Forms a complex with SV2B, syntaxin 1 and SNAP25.,
相关产品： YT4485,YT4484,YP0587,YP0586,KA4298C,KA1186C,KA1185C
细胞定位： Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .
组织表达： Expressed in melanocytes (PubMed:23999003).
科研货号： PLP000581

Synaptotagmin 1/2 (phospho Ser309/306) Polyclonal Antibody

Catalog No PLP000581

Product information

基因名称： SYT1/SYT2
蛋白名称： Synaptotagmin-1/2
Human_gene_id： 6857/127833
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6857
Human_swiss_prot_no： P21579/Q8N9I0
Human_swiss_link： http://www.uniprot.org/uniprotkb/P21579/entry
Mouse_gene_id： 20979/20980
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20979
Rat_gene_id： 25716/24805
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25716
Rat_swiss_prot_no： P21707/P29101
Rat_swiss_link： http://www.uniprot.org/uniprot/P21707
特异性： Phospho-Synaptotagmin 1/2 (S309/306) Polyclonal Antibody detects endogenous levels of Synaptotagmin 1/2 protein only when phosphorylated at S309/306.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SYT1; SVP65; SYT; Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT2; Synaptotagmin-2; Synaptotagmin II; SytII
实测条带： 47kD
功能： cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,domain:The first C2 domain mediates Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain mediates interaction with SV2A and STN2.,function:May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subcellular location:Synaptic vesicles and chromaffin granules.,subunit:Homotetramer (Probable). Interacts with SCAMP5, STN2, SV2A, SV2B, SV2C and RIMS1. Forms a complex with SV2B, syntaxin 1 and SNAP25.,
相关产品： YT4485,YT4484,YP0587,YP0586,KA4298C,KA1186C,KA1185C
细胞定位： Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane ; Single-pass membrane protein . Cytoplasm .
组织表达： Expressed in melanocytes (PubMed:23999003).
科研货号： PLP000581

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