Dab1 (phospho Tyr232) Polyclonal Antibody

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商品货号： PLP000517

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： DAB1
蛋白名称： Disabled homolog 1
Human_gene_id： 8674
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8674
Human_swiss_prot_no： O75553
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75553/entry
Mouse_gene_id： 13131
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13131
Mouse_swiss_prot_no： P97318
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97318
Rat_gene_id： 266729
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266729
Rat_swiss_prot_no： Q8CJH2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q8CJH2
特异性： Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DAB1; Disabled homolog 1
实测条带： 80kD
功能： domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： nucleolus,microtubule organizing center,cytosol,brush border,postsynaptic density,membrane,neuron projection,neuronal cell body,intracellular membrane-bounded organelle,apical part of cell,perinuclear region of cytoplasm,
组织表达： Mainly expressed in brain.
科研货号： PLP000517

Dab1 (phospho Tyr232) Polyclonal Antibody

Catalog No PLP000517

Product information

基因名称： DAB1
蛋白名称： Disabled homolog 1
Human_gene_id： 8674
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8674
Human_swiss_prot_no： O75553
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75553/entry
Mouse_gene_id： 13131
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13131
Mouse_swiss_prot_no： P97318
Mouse_swiss_link： http://www.uniprot.org/uniprot/P97318
Rat_gene_id： 266729
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266729
Rat_swiss_prot_no： Q8CJH2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q8CJH2
特异性： Phospho-Dab1 (Y232) Polyclonal Antibody detects endogenous levels of Dab1 protein only when phosphorylated at Y232.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： DAB1; Disabled homolog 1
实测条带： 80kD
功能： domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.,function:Adapter molecule functioning in neural development. May regulate SIAH1 activity.,PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.,similarity:Contains 1 PID domain.,subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： nucleolus,microtubule organizing center,cytosol,brush border,postsynaptic density,membrane,neuron projection,neuronal cell body,intracellular membrane-bounded organelle,apical part of cell,perinuclear region of cytoplasm,
组织表达： Mainly expressed in brain.
科研货号： PLP000517

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