MuSK (phospho Tyr755) Polyclonal Antibody

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商品货号： PLP000505

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MUSK
蛋白名称： Muscle, skeletal receptor tyrosine-protein kinase
Human_gene_id： 4593
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4593
Human_swiss_prot_no： O15146
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15146/entry
Mouse_gene_id： 18198
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18198
Mouse_swiss_prot_no： Q61006
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61006
Rat_gene_id： 81725
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81725
Rat_swiss_prot_no： Q62838
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62838
特异性： Phospho-MuSK (Y755) Polyclonal Antibody detects endogenous levels of MuSK protein only when phosphorylated at Y755.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor
实测条带： 97kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in MUSK is a cause of autosomal recessive congenital myasthenic syndrome (CMS) [MIM:608931]. Congenital myasthenic syndromes are inherited disorders of neuromuscular transmission that stem from mutations in presynaptic, synaptic, or postsynaptic proteins. MUSK mutations lead to decreased agrin-dependent AChR aggregation, a critical step in the formation of the neuromuscular junction.,function:Receptor tyrosine kinase that is a key mediator of agrin's action and is involved in neuromuscular junction (NMJ) organization.,online information:MuSK entry,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with DOK7, which probably regulates its activity.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .
科研货号： PLP000505

MuSK (phospho Tyr755) Polyclonal Antibody

Catalog No PLP000505

Product information

基因名称： MUSK
蛋白名称： Muscle, skeletal receptor tyrosine-protein kinase
Human_gene_id： 4593
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4593
Human_swiss_prot_no： O15146
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15146/entry
Mouse_gene_id： 18198
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18198
Mouse_swiss_prot_no： Q61006
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61006
Rat_gene_id： 81725
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=81725
Rat_swiss_prot_no： Q62838
Rat_swiss_link： http://www.uniprot.org/uniprot/Q62838
特异性： Phospho-MuSK (Y755) Polyclonal Antibody detects endogenous levels of MuSK protein only when phosphorylated at Y755.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor
实测条带： 97kD
功能： catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,disease:Defects in MUSK is a cause of autosomal recessive congenital myasthenic syndrome (CMS) [MIM:608931]. Congenital myasthenic syndromes are inherited disorders of neuromuscular transmission that stem from mutations in presynaptic, synaptic, or postsynaptic proteins. MUSK mutations lead to decreased agrin-dependent AChR aggregation, a critical step in the formation of the neuromuscular junction.,function:Receptor tyrosine kinase that is a key mediator of agrin's action and is involved in neuromuscular junction (NMJ) organization.,online information:MuSK entry,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 FZ (frizzled) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with DOK7, which probably regulates its activity.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .
科研货号： PLP000505

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