RPA p32 (phospho Ser33) Polyclonal Antibody

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商品货号： PLP000473

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： RPA2
蛋白名称： Replication protein A 32 kDa subunit
Human_gene_id： 6118
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6118
Human_swiss_prot_no： P15927
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15927/entry
Mouse_swiss_prot_no： Q62193
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62193
Rat_gene_id： 59102
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59102
Rat_swiss_prot_no： Q63528
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63528
特异性： Phospho-RPA p32 (S33) Polyclonal Antibody detects endogenous levels of RPA p32 protein only when phosphorylated at S33.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RPA2; REPA2; RPA32; RPA34; Replication protein A 32 kDa subunit; RP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34
实测条带： 32kD
信号通路： DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能： function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
相关产品： YT4170,YP0743,YP0476,KA4267C,KA1758C,KA1472C
细胞定位： Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
组织表达： Kidney,Lung,Muscle,
科研货号： PLP000473

RPA p32 (phospho Ser33) Polyclonal Antibody

Catalog No PLP000473

Product information

基因名称： RPA2
蛋白名称： Replication protein A 32 kDa subunit
Human_gene_id： 6118
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6118
Human_swiss_prot_no： P15927
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15927/entry
Mouse_swiss_prot_no： Q62193
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62193
Rat_gene_id： 59102
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59102
Rat_swiss_prot_no： Q63528
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63528
特异性： Phospho-RPA p32 (S33) Polyclonal Antibody detects endogenous levels of RPA p32 protein only when phosphorylated at S33.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RPA2; REPA2; RPA32; RPA34; Replication protein A 32 kDa subunit; RP-A p32; Replication factor A protein 2; RF-A protein 2; Replication protein A 34 kDa subunit; RP-A p34
实测条带： 32kD
信号通路： DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能： function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
相关产品： YT4170,YP0743,YP0476,KA4267C,KA1758C,KA1472C
细胞定位： Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
组织表达： Kidney,Lung,Muscle,
科研货号： PLP000473

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