FANCG (phospho Ser383) Polyclonal Antibody

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商品货号： PLP000452

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： FANCG
蛋白名称： Fanconi anemia group G protein
Human_gene_id： 2189
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2189
Human_swiss_prot_no： O15287
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15287/entry
Mouse_swiss_prot_no： Q9EQR6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EQR6
特异性： Phospho-FANCG (S383) Polyclonal Antibody detects endogenous levels of FANCG protein only when phosphorylated at S383.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： FANCG; XRCC9; Fanconi anemia group G protein; Protein FACG; DNA repair protein XRCC9
实测条带： 69kD
功能： disease:Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.,function:DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.,similarity:Contains 4 TPR repeats.,subcellular location:The major form is nuclear. The minor form is cytoplasmic.,subunit:Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients.,tissue specificity:Highly expressed in testis and thymus. Found in lymphoblasts.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . The major form is nuclear. The minor form is cytoplasmic.
组织表达： Highly expressed in testis and thymus. Found in lymphoblasts.
科研货号： PLP000452

FANCG (phospho Ser383) Polyclonal Antibody

Catalog No PLP000452

Product information

基因名称： FANCG
蛋白名称： Fanconi anemia group G protein
Human_gene_id： 2189
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2189
Human_swiss_prot_no： O15287
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15287/entry
Mouse_swiss_prot_no： Q9EQR6
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9EQR6
特异性： Phospho-FANCG (S383) Polyclonal Antibody detects endogenous levels of FANCG protein only when phosphorylated at S383.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： FANCG; XRCC9; Fanconi anemia group G protein; Protein FACG; DNA repair protein XRCC9
实测条带： 69kD
功能： disease:Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.,function:DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.,similarity:Contains 4 TPR repeats.,subcellular location:The major form is nuclear. The minor form is cytoplasmic.,subunit:Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients.,tissue specificity:Highly expressed in testis and thymus. Found in lymphoblasts.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . The major form is nuclear. The minor form is cytoplasmic.
组织表达： Highly expressed in testis and thymus. Found in lymphoblasts.
科研货号： PLP000452

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