HP1γ (phospho Ser93) Polyclonal Antibody

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商品货号： PLP000447

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CBX3
蛋白名称： Chromobox protein homolog 3
Human_gene_id： 11335/653972
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11335
Human_swiss_prot_no： Q13185
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13185/entry
Mouse_swiss_prot_no： P23198
Mouse_swiss_link： http://www.uniprot.org/uniprot/P23198
特异性： Phospho-HP1γ (S93) Polyclonal Antibody detects endogenous levels of HP1γ protein only when phosphorylated at S93.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein
实测条带： 24kD
功能： function:Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.,PTM:Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.,similarity:Contains 2 chromo domains.,subcellular location:Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.,subunit:Binds directly to CHAF1A. Interacts with histone H3 methylated at 'Lys-9'. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with LBR, INCENP, TRIM28/TIF1B, SUV420H1, SUV420H2 and SP100. Interacts with TIF1A (By similarity). Interacts with MIS12 and C20orf127. Can interact directly with CBX5 via the chromoshadow domain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). .
组织表达： Bone marrow,Brain,Cajal-Retzius cell,Epithelium,Liver,Placenta,
tag： hot
科研货号： PLP000447

HP1γ (phospho Ser93) Polyclonal Antibody

Catalog No PLP000447

Product information

基因名称： CBX3
蛋白名称： Chromobox protein homolog 3
Human_gene_id： 11335/653972
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11335
Human_swiss_prot_no： Q13185
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13185/entry
Mouse_swiss_prot_no： P23198
Mouse_swiss_link： http://www.uniprot.org/uniprot/P23198
特异性： Phospho-HP1γ (S93) Polyclonal Antibody detects endogenous levels of HP1γ protein only when phosphorylated at S93.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein
实测条带： 24kD
功能： function:Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.,PTM:Phosphorylated by PIM1. Phosphorylated during interphase and possibly hyper-phosphorylated during mitosis.,similarity:Contains 2 chromo domains.,subcellular location:Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis.,subunit:Binds directly to CHAF1A. Interacts with histone H3 methylated at 'Lys-9'. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with LBR, INCENP, TRIM28/TIF1B, SUV420H1, SUV420H2 and SP100. Interacts with TIF1A (By similarity). Interacts with MIS12 and C20orf127. Can interact directly with CBX5 via the chromoshadow domain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). .
组织表达： Bone marrow,Brain,Cajal-Retzius cell,Epithelium,Liver,Placenta,
tag： hot
科研货号： PLP000447

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