CD40 (phospho Thr254) Polyclonal Antibody

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商品货号： PLP000376

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CD40
蛋白名称： Tumor necrosis factor receptor superfamily member 5
Human_gene_id： 958
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=958
Human_swiss_prot_no： P25942
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25942/entry
Mouse_gene_id： 21939
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21939
Mouse_swiss_prot_no： P27512
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27512
特异性： Phospho-CD40 (T254) Polyclonal Antibody detects endogenous levels of CD40 protein only when phosphorylated at T254.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
实测条带： 30kD
信号通路： Cytokine-cytokine receptor interaction;Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Asthma;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Primary immunodeficiency;Viral myocarditis;
功能： alternative products:Additional isoforms seem to exist,disease:Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3) [MIM:606843]. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.,function:Receptor for TNFSF5/CD40LG.,online information:CD40 entry,online information:CD40 mutation db,similarity:Contains 4 TNFR-Cys repeats.,subunit:Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.,tissue specificity:B-cells and in primary carcinomas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
组织表达： B-cells and in primary carcinomas.
科研货号： PLP000376

CD40 (phospho Thr254) Polyclonal Antibody

Catalog No PLP000376

Product information

基因名称： CD40
蛋白名称： Tumor necrosis factor receptor superfamily member 5
Human_gene_id： 958
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=958
Human_swiss_prot_no： P25942
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25942/entry
Mouse_gene_id： 21939
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21939
Mouse_swiss_prot_no： P27512
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27512
特异性： Phospho-CD40 (T254) Polyclonal Antibody detects endogenous levels of CD40 protein only when phosphorylated at T254.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
实测条带： 30kD
信号通路： Cytokine-cytokine receptor interaction;Cell adhesion molecules (CAMs);Toll_Like;Intestinal immune network for IgA production;Asthma;Autoimmune thyroid disease;Systemic lupus erythematosus;Allograft rejection;Primary immunodeficiency;Viral myocarditis;
功能： alternative products:Additional isoforms seem to exist,disease:Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3) [MIM:606843]. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation.,function:Receptor for TNFSF5/CD40LG.,online information:CD40 entry,online information:CD40 mutation db,similarity:Contains 4 TNFR-Cys repeats.,subunit:Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.,tissue specificity:B-cells and in primary carcinomas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： [Isoform I]: Cell membrane; Single-pass type I membrane protein.; [Isoform II]: Secreted.
组织表达： B-cells and in primary carcinomas.
科研货号： PLP000376

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