Vav (phospho Tyr174) Polyclonal Antibody

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商品货号： PLP000270

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： VAV1
蛋白名称： Proto-oncogene vav
Human_gene_id： 7409
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7409
Human_swiss_prot_no： P15498
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15498/entry
Mouse_gene_id： 22324
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22324
Mouse_swiss_prot_no： P27870
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27870
Rat_swiss_prot_no： P54100
Rat_swiss_link： http://www.uniprot.org/uniprot/P54100
特异性： Phospho-Vav (Y174) Polyclonal Antibody detects endogenous levels of Vav protein only when phosphorylated at Y174.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VAV1; VAV; Proto-oncogene vav
实测条带： 100kD
信号通路： Chemokine;Focal adhesion;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;
功能： domain:The DH domain is involved in interaction with CCPG1.,function:Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.,miscellaneous:'Vav' stands for the sixth letter of the Hebrew alphabet.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:May interact with CCPG1 (By similarity). Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK.,tissue specificity:Widely expressed in hematopoietic cells but not in other cell types.,
相关产品： YT5041,YT4863,YT4862,YP0969,YP0274,YP0273,KA4316C,KA1228C
细胞定位： intracellular,cytosol,plasma membrane,cell-cell junction,
组织表达： Widely expressed in hematopoietic cells but not in other cell types.
科研货号： PLP000270

Vav (phospho Tyr174) Polyclonal Antibody

Catalog No PLP000270

Product information

基因名称： VAV1
蛋白名称： Proto-oncogene vav
Human_gene_id： 7409
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7409
Human_swiss_prot_no： P15498
Human_swiss_link： http://www.uniprot.org/uniprotkb/P15498/entry
Mouse_gene_id： 22324
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22324
Mouse_swiss_prot_no： P27870
Mouse_swiss_link： http://www.uniprot.org/uniprot/P27870
Rat_swiss_prot_no： P54100
Rat_swiss_link： http://www.uniprot.org/uniprot/P54100
特异性： Phospho-Vav (Y174) Polyclonal Antibody detects endogenous levels of Vav protein only when phosphorylated at Y174.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： VAV1; VAV; Proto-oncogene vav
实测条带： 100kD
信号通路： Chemokine;Focal adhesion;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Fc gamma R-mediated phagocytosis;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;
功能： domain:The DH domain is involved in interaction with CCPG1.,function:Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.,miscellaneous:'Vav' stands for the sixth letter of the Hebrew alphabet.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 SH2 domain.,similarity:Contains 2 SH3 domains.,subunit:May interact with CCPG1 (By similarity). Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK.,tissue specificity:Widely expressed in hematopoietic cells but not in other cell types.,
相关产品： YT5041,YT4863,YT4862,YP0969,YP0274,YP0273,KA4316C,KA1228C
细胞定位： intracellular,cytosol,plasma membrane,cell-cell junction,
组织表达： Widely expressed in hematopoietic cells but not in other cell types.
科研货号： PLP000270

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