Sp1 (phospho Thr453) Polyclonal Antibody

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商品货号： PLP000244

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SP1
蛋白名称： Transcription factor Sp1
Human_gene_id： 6667
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6667
Human_swiss_prot_no： P08047
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08047/entry
Mouse_gene_id： 20683
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20683
Mouse_swiss_prot_no： O89090
Mouse_swiss_link： http://www.uniprot.org/uniprot/O89090
Rat_gene_id： 24790
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24790
Rat_swiss_prot_no： Q01714
Rat_swiss_link： http://www.uniprot.org/uniprot/Q01714
特异性： Phospho-Sp1 (T453) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T453.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SP1; TSFP1; Transcription factor Sp1
实测条带： 90kD
信号通路： TGF-beta;Huntington's disease;
功能： function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.,PTM:O-glycosylated; contains N-acetylglucosamine side chains.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.,
相关产品： YT4373,YT4372,YP0248,YP0247,KA3174C,KA3173C,KA1141C,KA1140C
细胞定位： Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
组织表达： Up-regulated in adenocarcinomas of the stomach (at protein level). Isoform 3 is ubiquitously expressed at low levels.
科研货号： PLP000244

Sp1 (phospho Thr453) Polyclonal Antibody

Catalog No PLP000244

Product information

基因名称： SP1
蛋白名称： Transcription factor Sp1
Human_gene_id： 6667
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6667
Human_swiss_prot_no： P08047
Human_swiss_link： http://www.uniprot.org/uniprotkb/P08047/entry
Mouse_gene_id： 20683
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20683
Mouse_swiss_prot_no： O89090
Mouse_swiss_link： http://www.uniprot.org/uniprot/O89090
Rat_gene_id： 24790
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24790
Rat_swiss_prot_no： Q01714
Rat_swiss_link： http://www.uniprot.org/uniprot/Q01714
特异性： Phospho-Sp1 (T453) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T453.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SP1; TSFP1; Transcription factor Sp1
实测条带： 90kD
信号通路： TGF-beta;Huntington's disease;
功能： function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Can interact with G/C-rich motifs from serotonin receptor promoter.,PTM:O-glycosylated; contains N-acetylglucosamine side chains.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with ATF7IP, ATF7IP2, POGZ, HCFC1, AATF and PHC2. Interacts with varicella-zoster virus IE62 protein and HIV-1 Vpr. Interacts with SV40 VP2/3 proteins. Interacts with SV40 major capsid protein VP1; this interaction leads to a cooperativity between the two proteins in DNA binding.,
相关产品： YT4373,YT4372,YP0248,YP0247,KA3174C,KA3173C,KA1141C,KA1140C
细胞定位： Nucleus. Cytoplasm. Nuclear location is governed by glycosylated/phosphorylated states. Insulin promotes nuclear location, while glucagon favors cytoplasmic location.
组织表达： Up-regulated in adenocarcinomas of the stomach (at protein level). Isoform 3 is ubiquitously expressed at low levels.
科研货号： PLP000244

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