p21 (phospho Thr145) Polyclonal Antibody

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商品货号： PLP000197

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CDKN1A
蛋白名称： Cyclin-dependent kinase inhibitor 1
Human_gene_id： 1026
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1026
Human_swiss_prot_no： P38936
Human_swiss_link： http://www.uniprot.org/uniprotkb/P38936/entry
Mouse_gene_id： 12575
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12575
Mouse_swiss_prot_no： P39689
Mouse_swiss_link： http://www.uniprot.org/uniprot/P39689
特异性： Phospho-p21 (T145) Polyclonal Antibody detects endogenous levels of p21 protein only when phosphorylated at T145.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21
分子量： 18kD
信号通路： Stem cell pathway; ErbB/HER; PI3K/Akt; AMPK; Cell_Cycle_G1S;Cell_Cycle_G2M_DNA; Protein_Acetylation
功能： function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus .
组织表达： Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
科研货号： PLP000197

p21 (phospho Thr145) Polyclonal Antibody

Catalog No PLP000197

Product information

基因名称： CDKN1A
蛋白名称： Cyclin-dependent kinase inhibitor 1
Human_gene_id： 1026
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1026
Human_swiss_prot_no： P38936
Human_swiss_link： http://www.uniprot.org/uniprotkb/P38936/entry
Mouse_gene_id： 12575
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12575
Mouse_swiss_prot_no： P39689
Mouse_swiss_link： http://www.uniprot.org/uniprot/P39689
特异性： Phospho-p21 (T145) Polyclonal Antibody detects endogenous levels of p21 protein only when phosphorylated at T145.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21
分子量： 18kD
信号通路： Stem cell pathway; ErbB/HER; PI3K/Akt; AMPK; Cell_Cycle_G1S;Cell_Cycle_G2M_DNA; Protein_Acetylation
功能： function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus .
组织表达： Expressed in all adult tissues, with 5-fold lower levels observed in the brain.
科研货号： PLP000197

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